Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.50 |
| ▸ | GLA | P06280 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | CASP7 | P55210 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2425524 | 0.85 | MAOB (0.53) | KDM4EALDH1A1GAAPOLBMAPT | |
| SCHEMBL2424066 | 0.82 | KDM4E (0.46) | KDM4EALDH1A1GAACA12CA9 | |
| SCHEMBL2427139 | 0.78 | HPGD (0.49) | KDM4EALDH1A1CA12CA9MAPT | |
| SCHEMBL2430119 | 0.78 | ALDH1A1 (0.49) | KDM4EALDH1A1GAAPOLBTDP1 | |
| SCHEMBL2429282 | 0.76 | ALDH1A1 (0.41) | KDM4EGLAALDH1A1GAACA12 | |
| SCHEMBL11179993 | 0.75 | KDM4E (0.65) | KDM4EGLAALDH1A1GAACA12 | |
| SCHEMBL2427801 | 0.75 | ALDH1A1 (0.52) | KDM4EALDH1A1GAAPOLBMAPT | |
| SCHEMBL2422437 | 0.72 | KDM4E (0.49) | KDM4EALDH1A1GAACA12CA9 | |
| SCHEMBL4172232 | 0.71 | MAPT (0.74) | KDM4EGLAALDH1A1CA12CA9 | |
| SCHEMBL12325498 | 0.71 | KDM4E (0.56) | KDM4EGLAALDH1A1GAACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2368895-A1 | Ferrocenyl flavonoids | Centre National de la Recherche Scientifique (CNRS) (FR) | 2011-09-28 | — | — | EP | disclosed |
| WO-2011107572-A1 | FERROCENYL FLAVONOIDS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2011-09-09 | — | — | WO | disclosed |