Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.74 |
| ▸ | TP53 | P04637 | 4/20 | 0.74 |
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.71 |
| ▸ | TNKS | O95271 | 2/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.64 |
| ▸ | MAOB | P27338 | 3/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.62 |
| ▸ | CA12 | O43570 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.62 |
| ▸ | CA9 | Q16790 | 2/20 | 0.62 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28635129 | 0.91 | ABCB1 (0.71) | MAPTSMN1; SMN2CYP3A4TP53MEN1 | |
| SCHEMBL31499219 | 0.88 | CYP3A4 (0.77) | MAPTSMN1; SMN2CYP3A4TP53MEN1 | |
| SCHEMBL28547386 | 0.88 | CYP3A4 (0.74) | MAPTSMN1; SMN2CYP3A4TP53MEN1 | |
| SCHEMBL13609780 | 0.87 | CYP3A4 (0.67) | MAPTSMN1; SMN2CYP3A4TP53MEN1 | |
| Acetic Acid SCHEMBL311830 | 0.87 | TNKS (0.67) | MAPTSMN1; SMN2CYP3A4TP53MEN1 | |
| SCHEMBL311927 | 0.86 | TNKS (0.71) | MAPTSMN1; SMN2CYP3A4TP53MEN1 | |
| SCHEMBL29887764 | 0.86 | TNKS (0.71) | MAPTSMN1; SMN2CYP3A4TP53MEN1 | |
| SCHEMBL7948102 | 0.85 | KMT2A (0.68) | MAPTSMN1; SMN2CYP3A4TP53MEN1 | |
| SCHEMBL30540840 | 0.85 | SMN1; SMN2 (1.00) | MAPTSMN1; SMN2CYP3A4TP53MEN1 | |
| SCHEMBL27493025 | 0.85 | SMN1; SMN2 (1.00) | MAPTSMN1; SMN2CYP3A4TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090130051-A1 | Flavonoid Compounds and Uses Thereof | HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINE (AU) | 2009-05-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090130051-A1 | Flavonoid Compounds and Uses Thereof | CAT, NQO1, GPX4 | MAPT 3887/4885SMN1; SMN2 1615/4885CYP3A4 518/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.