Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | CNR2 | P34972 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.54 |
| ▸ | TUBB | P07437 | 1/20 | 0.54 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.54 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.54 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.54 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.54 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.54 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.54 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.54 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.54 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.54 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.54 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.54 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.54 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.54 |
| ▸ | F10 | P00742 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24273338 | 0.90 | CNR2 (0.56) | CNR1CNR2KLKB1TUBB4ATUBB | |
| SCHEMBL24273335 | 0.86 | HPGD (0.55) | LMNAKLKB1F10NPC1RAB9A | |
| SCHEMBL24273550 | 0.81 | CNR2 (0.56) | CNR1CNR2LMNAKLKB1MAPK1 | |
| SCHEMBL24273556 | 0.81 | TUBB4A (0.63) | CNR1CNR2LMNATUBB4ATUBB | |
| SCHEMBL15908288 | 0.81 | TUBB4A (0.82) | CNR1CNR2LMNATUBB4ATUBB | |
| SCHEMBL24273345 | 0.80 | SLC22A12 (0.52) | CNR1CNR2LMNAKLKB1NPC1 | |
| SCHEMBL24273190 | 0.79 | POLB (0.54) | CNR2LMNATUBB4ATUBBTUBA3C | |
| SCHEMBL24273081 | 0.79 | HDAC1 (0.48) | CNR1CNR2LMNAKLKB1MAPK1 | |
| SCHEMBL31693410 | 0.78 | TP53 (0.67) | CNR1CNR2LMNAMAPK1TP53 | |
| SCHEMBL24273316 | 0.78 | KLKB1 (0.50) | LMNAKLKB1F10NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022061008-A2 | MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X4 AND RELATED PRODUCTS AND METHODS | ESCIENT PHARMACEUTICALS, INC. (US) | 2022-03-24 | — | — | WO | disclosed |