Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | TPO | P07202 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LPO | P22079 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10399847 | 0.87 | HCAR2 (0.54) | HCAR2HCAR3ALDH1A1 | |
| SCHEMBL12200985 | 0.85 | HCAR2 (0.46) | HCAR2KDM4ECCNA2CDK2CCNA1 | |
| SCHEMBL14714005 | 0.78 | MEN1 (0.30) | KDM4EALDH1A1APOBEC3GTSHRCYP2C19 | |
| SCHEMBL173914 | 0.78 | HCAR2 (0.47) | HCAR2KDM4EALDH1A1GLA | |
| SCHEMBL16622728 | 0.75 | LMNA (0.35) | — | |
| SCHEMBL2427435 | 0.75 | — | — | |
| SCHEMBL27683382 | 0.74 | CYP1A2 (0.38) | HCAR2KDM4ECDK2ALDH1A1TSHR | |
| SCHEMBL28079252 | 0.71 | HCAR2 (0.32) | HCAR2 | |
| SCHEMBL12197657 | 0.70 | ALDH1A1 (0.41) | NPBWR1ALDH1A1 | |
| Ethane SCHEMBL28967597 | 0.69 | HPGD (0.39) | KDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025038863-A1 | INDOLE AND PYRROLOYPYRIDINE DERIVATIVES AS GPR17 MODULATORS | BIOGEN MA INC. (US) | 2025-02-20 | — | — | WO | disclosed |