Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABAT | P80404 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | LOXL2 | Q9Y4K0 | 7/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | F11 | P03951 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 2/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1079226 | 0.80 | TAAR1 (0.56) | LOXL2TAAR1NOS3NOS1NOS2 | |
| SCHEMBL17934442 | 0.77 | ENPP2 (0.54) | ABATLOXL2NOS3NOS1NOS2 | |
| SCHEMBL15828 | 0.76 | HRH3 (0.79) | ABATHRH3LOXL2F10F11 | |
| SCHEMBL8283253 | 0.76 | TSHR (0.46) | NOS3NOS1CA12CA1CA2 | |
| SCHEMBL8289155 | 0.74 | HRH3 (0.50) | ABATHRH3LOXL2F10F11 | |
| SCHEMBL14436411 | 0.74 | LPL (0.46) | TAAR1CA2 | |
| Methyl Alcohol SCHEMBL22528993 | 0.74 | ABAT (0.67) | ABATHRH3LOXL2F10F11 | |
| Bromide SCHEMBL29198706 | 0.73 | HRH3 (0.73) | ABATHRH3LOXL2F10F11 | |
| Iodide SCHEMBL28395414 | 0.73 | HRH3 (0.73) | ABATHRH3LOXL2F10F11 | |
| Hydrochloric Acid SCHEMBL3168189 | 0.73 | HRH3 (0.73) | ABATHRH3LOXL2F10F11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022048470-A1 | MESOPOROUS SILICA NANOPARTICLE CONTROLLED RELEASE SYSTEM, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 华东理工大学 | 2022-03-10 | — | — | WO | disclosed |
| CN-1204126-C | Process for preparing pyridazin-2-one derivs. | SUMITOMO CHEMICAL CO (JP) | 2005-06-01 | — | — | CN | disclosed |
| CN-1334805-A | Process for preparing pyridazin-2-one derivs. | SUMITOMO CHEMICAL CO (JP) | 2002-02-06 | — | — | CN | disclosed |