Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24277079 | 0.79 | CYP1A2 (0.38) | KDM4ELMNACACNA1HCACNA1BCACNA1C | |
| SCHEMBL24276959 | 0.79 | KDM4E (0.39) | KDM4ELMNACACNA1HCACNA1BCACNA1C | |
| SCHEMBL24276960 | 0.79 | KDM4E (0.41) | KDM4ELMNACACNA1HCACNA1BCACNA1C | |
| SCHEMBL5258122 | 0.68 | MAPK14 (0.48) | KDM4ELMNACYP1A2GRM2 | |
| SCHEMBL18854481 | 0.67 | EPAS1 (0.43) | CACNA1HCACNA1BCACNA1CL3MBTL1EPAS1 | |
| SCHEMBL7856762 | 0.66 | IDO1 (0.42) | KDM4ELMNACYP1A2KDM4AAAK1 | |
| SCHEMBL22664604 | 0.65 | RPS6KA1 (0.43) | L3MBTL1EPAS1CA12CA1CA2 | |
| SCHEMBL31716307 | 0.65 | EPAS1 (0.45) | KDM4ELMNACACNA1HCACNA1BCACNA1C | |
| SCHEMBL22664847 | 0.65 | AAK1 (0.45) | KDM4ELMNACACNA1HCACNA1BCACNA1C | |
| SCHEMBL17664632 | 0.65 | AAK1 (0.42) | KDM4ELMNACACNA1HCACNA1BCACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022052958-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2022-03-17 | — | — | WO | disclosed |