Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.35 |
| ▸ | ACACA | Q13085 | 2/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP1 | P63208 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 1/20 | 0.33 |
| ▸ | GRK2 | P25098 | 1/20 | 0.33 |
| ▸ | GRK3 | P35626 | 1/20 | 0.33 |
| ▸ | GRK7 | Q8WTQ7 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24276958 | 0.79 | KDM4E (0.41) | CYP1A2GFERHSD17B10L3MBTL1KDM4E | |
| SCHEMBL24276959 | 0.71 | KDM4E (0.39) | CYP1A2GFERHSD17B10L3MBTL1KDM4E | |
| SCHEMBL24276960 | 0.71 | KDM4E (0.41) | CYP1A2GFERHSD17B10L3MBTL1KDM4E | |
| SCHEMBL18041432 | 0.67 | HDAC1 (0.44) | HDAC1L3MBTL1KDM4AACACBACACA | |
| SCHEMBL7856762 | 0.66 | IDO1 (0.42) | CYP1A2KDM4ELMNAKDM4AACACB | |
| SCHEMBL25546386 | 0.65 | ALDH1A1 (0.52) | CYP1A2KDM4ELMNAROCK2PARP1 | |
| SCHEMBL29187575 | 0.64 | MAPKAPK2 (0.41) | KDM4ELMNANAMPTAAK1 | |
| SCHEMBL30433088 | 0.64 | MAPKAPK2 (0.41) | KDM4ELMNANAMPTAAK1 | |
| SCHEMBL5258122 | 0.64 | MAPK14 (0.48) | CYP1A2KDM4ELMNAROCK2GRK2 | |
| SCHEMBL23118474 | 0.63 | MEN1 (0.41) | HDAC1KDM4EKDM4AALDH1A1AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022052958-A1 | HETEROCYCLIC GLP-1 AGONISTS | GASHERBRUM BIO, INC. (US) | 2022-03-17 | — | — | WO | disclosed |