SCHEMBL24277643

SCHEMBL24277643

c1ccc2cc(-c3ccc(N(c4ccc5c(c4)Oc4cccc6cccc(c46)O5)c4cccc5ccccc45)cc3)ccc2c1

nearest known ligand 0.33

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
KDM4E B2RXH2 1/20 0.32
MAPK1 P28482 1/20 0.32
ATM Q13315 1/20 0.32
HSD17B1 P14061 1/20 0.31
HSD17B2 P37059 1/20 0.31
CYP1A1 P04798 1/20 0.30
CYP1B1 Q16678 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24277624 0.92 KDM4E (0.34) KDM4EMAPK1ATMCYP1A1
SCHEMBL24277355 0.89 ESR1 (0.38) ESR1ESR2KDM4EMAPK1ATM
SCHEMBL24277710 0.89 ESR1 (0.31) ESR1ESR2KDM4EMAPK1ATM
SCHEMBL24277688 0.89 KDM4E (0.38) KDM4EMAPK1ATM
SCHEMBL24277678 0.88 CA12 (0.37) ESR1ESR2KDM4EMAPK1ATM
SCHEMBL24277334 0.87 KDM4E (0.38) KDM4EMAPK1ATM
SCHEMBL24277708 0.87 ESR1 (0.36) ESR1ESR2KDM4EMAPK1ATM
SCHEMBL24277622 0.87 ESR1 (0.36) ESR1ESR2KDM4EMAPK1ATM
SCHEMBL24277630 0.87 HSD17B1 (0.38) ESR1ESR2KDM4EMAPK1ATM
SCHEMBL18563220 0.87 SIGMAR1 (0.33) CYP1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022050533-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2022-03-10 WO disclosed