Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 4/20 | 0.46 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 9/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.40 |
| ▸ | AR | P10275 | 4/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22839368 | 0.91 | HSD17B1 (0.40) | HSD17B1CYP17A1ESR1ESR2AR | |
| SCHEMBL25998371 | 0.87 | ALDH1A1 (0.49) | HSD17B1ESR1ESR2ARBACE1 | |
| SCHEMBL10445995 | 0.87 | HSD17B1 (0.48) | HSD17B1CYP17A1ESR1ESR2AR | |
| SCHEMBL1758246 | 0.87 | ESR1 (0.50) | HSD17B1ESR1ESR2BACE1HSP90AA1 | |
| SCHEMBL16790388 | 0.82 | ESR1 (0.43) | HSD17B1ESR1ESR2ARBACE1 | |
| SCHEMBL1596751 | 0.81 | TP53 (0.52) | HSD17B1ESR1ESR2ARHSD17B2 | |
| SCHEMBL12922915 | 0.80 | HSD17B1 (0.51) | HSD17B1CYP17A1ESR1ESR2HSD17B2 | |
| SCHEMBL9608273 | 0.80 | ESR1 (0.50) | ESR1ESR2ARTP53TDP1 | |
| SCHEMBL3325227 | 0.80 | ESR1 (0.44) | HSD17B1ESR1ESR2BACE1HSP90AA1 | |
| SCHEMBL29465801 | 0.79 | TP53 (0.54) | HSD17B1ESR1ESR2ARHSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974904-A1 | PHOTOSENSITIVE RESIN COMPOSITION, PATTERNING PROCESS, METHOD FOR FORMING CURED FILM, INTERLAYER INSULATION FILM, SURFACE PROTECTIVE FILM, AND ELECTRONIC COMPONENT | Shin-Etsu Chemical Co., Ltd. (JP) | 2022-03-30 | — | — | EP | disclosed |