Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PAX2 | Q02962 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24284140 | 0.82 | MBOAT4 (0.36) | ALDH1A1EGLN2HSD17B10ENPP1USP2 | |
| SCHEMBL24386972 | 0.71 | ALDH1A1 (0.36) | ALDH1A1EGLN2HSD17B10ENPP1TSHR | |
| SCHEMBL17430752 | 0.70 | EGLN2 (0.42) | ALDH1A1EGLN2HSD17B10ENPP1TSHR | |
| SCHEMBL6116929 | 0.70 | ALDH1A1 (0.38) | ALDH1A1EGLN2 | |
| SCHEMBL24284144 | 0.68 | TSHR (0.38) | ALDH1A1EGLN2HSD17B10ENPP1USP2 | |
| SCHEMBL19560782 | 0.65 | EGLN2 (0.36) | ALDH1A1EGLN2ENPP1KDM4EPKM | |
| SCHEMBL23029829 | 0.65 | EGLN2 (0.36) | ALDH1A1EGLN2ENPP1TSHRKDM4E | |
| SCHEMBL19761056 | 0.65 | EGLN2 (0.36) | ALDH1A1EGLN2ENPP1TSHRL3MBTL1 | |
| SCHEMBL14122422 | 0.65 | ALDH1A1 (0.40) | ALDH1A1HSD17B10ENPP1HPGDHTT | |
| SCHEMBL353089 | 0.64 | HSD17B10 (0.55) | ALDH1A1HSD17B10ENPP1USP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022042331-A1 | HETEROCYCLIC COMPOUND, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2022-03-03 | — | — | WO | disclosed |