SCHEMBL24284657

SCHEMBL24284657

N/C=C/c1ccccc1/C=C/C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 2/20 0.62
CA1 P00915 1/20 0.62
CA2 P00918 1/20 0.62
CA4 P22748 1/20 0.62
HCAR2 Q8TDS4 2/20 0.54
HDAC3 O15379 1/20 0.54
TNKS O95271 1/20 0.54
HDAC4 P56524 1/20 0.54
HDAC1 Q13547 1/20 0.54
HDAC7 Q8WUI4 1/20 0.54
HDAC2 Q92769 1/20 0.54
HDAC10 Q969S8 1/20 0.54
HDAC11 Q96DB2 1/20 0.54
HDAC8 Q9BY41 1/20 0.54
TNKS2 Q9H2K2 1/20 0.54
HDAC6 Q9UBN7 1/20 0.54
HDAC9 Q9UKV0 1/20 0.54
HDAC5 Q9UQL6 1/20 0.54
HTT P42858 1/20 0.53
MAPT P10636 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL459291 0.89 NFKB1 (0.75) NFKB1CA1CA2CA4HCAR2
SCHEMBL69543 0.89 NFKB1 (0.75) NFKB1CA1CA2CA4HCAR2
SCHEMBL31197561 0.89 NFKB1 (0.75) NFKB1CA1CA2CA4HCAR2
Bromide SCHEMBL8376004 0.87 NFKB1 (0.72) NFKB1CA1CA2CA4HCAR2
Hydrochloric Acid SCHEMBL8374050 0.87 NFKB1 (0.72) NFKB1CA1CA2CA4HCAR2
SCHEMBL2313844 0.81 NFKB1 (0.64) NFKB1CA1CA2CA4HCAR2
SCHEMBL11121643 0.81 HCAR2 (0.75) NFKB1CA1CA2CA4HCAR2
SCHEMBL2313840 0.81 NFKB1 (0.64) NFKB1CA1CA2CA4HCAR2
SCHEMBL30451096 0.81 NFKB1 (0.64) NFKB1CA1CA2CA4HCAR2
SCHEMBL175543 0.79 NFKB1 (0.62) NFKB1CA1CA2CA4HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3626708-B1 ORGANIC COMPOUND, ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY APPARATUS, IMAGE PICKUP APPARATUS, ELECTRONIC APPARATUS, AND MOVING OBJECT CANON KK (JP) 2022-03-16 EP disclosed