Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.43 |
| ▸ | GRM2 | Q14416 | 6/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.36 |
| ▸ | RELA | Q04206 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14268238 | 0.88 | GRM2 (0.47) | GRM2DHODHCYP11B1CYP11B2NPC1 | |
| SCHEMBL25100819 | 0.82 | GRM2 (0.51) | GRM2DHODHCYP11B1CYP11B2NPC1 | |
| SCHEMBL15602058 | 0.81 | GRM2 (0.45) | GRM2DHODHCYP11B1CYP11B2NPC1 | |
| SCHEMBL8515855 | 0.80 | SMN1; SMN2 (0.55) | GRM2DHODHCYP11B1CYP11B2NPC1 | |
| SCHEMBL2430228 | 0.78 | ALOX5AP (0.43) | ALOX5APGRM2DHODHL3MBTL1CASP3 | |
| SCHEMBL15060602 | 0.77 | GRM2 (0.47) | ALOX5APGRM2DHODHCYP11B1CYP11B2 | |
| SCHEMBL25100958 | 0.75 | LPL (0.37) | GRM2DHODHCYP11B1CYP11B2NPC1 | |
| SCHEMBL20019514 | 0.74 | NPC1 (0.42) | ALOX5APGRM2DHODHCYP11B1NPC1 | |
| SCHEMBL13017141 | 0.73 | GRM2 (0.45) | ALOX5APGRM2DHODHCYP11B1CYP11B2 | |
| SCHEMBL9325558 | 0.72 | SMN1; SMN2 (0.55) | ALOX5APGRM2CYP11B1CYP11B2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546284-B1 | REACTIVE DENDRIMERS | UNIV OXFORD INNOVATION LTD (GB) | 2018-04-04 | — | — | EP | disclosed |
| US-8025988-B2 | Reactive organometallic dendrimers | ISIS INNOVATION LIMITED (GB) | 2011-09-27 | — | — | US | disclosed |
| US-20100228022-A1 | Reactive Organometallic Dendrimers | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2010-09-09 | — | — | US | disclosed |
| US-7740954-B2 | Reactive dendrimers | ISIS INNOVATION LIMITED (GB) | 2010-06-22 | — | — | US | disclosed |
| US-20050164029-A1 | Reactive dendrimers | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2005-07-28 | — | — | US | disclosed |
| EP-1546284-A1 | REACTIVE DENDRIMERS | ISIS INNOVATION LIMITED (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004020547-A1 | REACTIVE DENDRIMERS | ISIS INNOVATION LIMITED (GB) | 2004-03-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100228022-A1 | Reactive Organometallic Dendrimers | ITGAM, CD40LG, DBN1 | ALOX5AP 328/4885GRM2 44/4885DHODH 1172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.