SCHEMBL2428609

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2432620	1.00	PTPN2 (0.42)	PTPN2PTPN11DGAT1KDM4EPTPN1
	SCHEMBL2430785	0.92	MEN1 (0.48)	DGAT1KMT2AMEN1POLBMAPT
	SCHEMBL2430782	0.92	MEN1 (0.48)	DGAT1KMT2AMEN1POLBMAPT
	SCHEMBL2494789	0.92	KDM4E (0.47)	PTPN2PTPN11DGAT1KDM4EPTPN1
	SCHEMBL2494792	0.92	KDM4E (0.47)	PTPN2PTPN11DGAT1KDM4EPTPN1
	SCHEMBL2158018	0.90	IKBKB (0.44)	KDM4EPTPN1MAPTNPC1RAB9A
	SCHEMBL2433060	0.90	DGAT1 (0.45)	DGAT1ACKR3KMT2AMEN1POLB
	SCHEMBL2433058	0.90	DGAT1 (0.45)	DGAT1ACKR3KMT2AMEN1POLB
	SCHEMBL2437167	0.89	RAB9A (0.40)	DGAT1KDM4EKMT2AMEN1POLB
	SCHEMBL2428384	0.89	RAB9A (0.40)	DGAT1KDM4EKMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.