Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 19/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | PKLR | P30613 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.49 |
| ▸ | RORA | P35398 | 1/20 | 0.49 |
| ▸ | RORB | Q92753 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18312995 | 0.96 | RORC (0.62) | RORCPKMPKLRNR1I2RORA | |
| SCHEMBL24286431 | 0.92 | RORC (0.62) | RORCPKMPKLRNR1I2RORA | |
| SCHEMBL24286390 | 0.92 | PKM (0.57) | RORCPKMPKLR | |
| SCHEMBL24286649 | 0.92 | RORC (0.56) | RORCPKMPKLRNR1I2RORA | |
| SCHEMBL24286283 | 0.92 | RORC (0.56) | RORCPKMPKLRNR1I2RORA | |
| SCHEMBL24286804 | 0.89 | RORC (0.54) | RORCPKMPKLR | |
| SCHEMBL24286172 | 0.89 | RORC (0.66) | RORCPKMPKLRNR1I2RORA | |
| SCHEMBL24841305 | 0.89 | RORC (0.59) | RORCPKMPKLRNR1I2RORA | |
| SCHEMBL24286701 | 0.88 | PKM (0.53) | RORCPKMPKLRNR1I2 | |
| SCHEMBL18312797 | 0.88 | RORC (0.74) | RORCNR1I2RORARORB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023274396-A1 | BENZAZEPINE HETEROCYCLIC COMPOUND AND APPLICATION THEREOF IN MEDICINE | 广东东阳光药业有限公司 | 2023-01-05 | — | — | WO | disclosed |
| EP-3307738-B1 | ARYL DIHYDRO-2H-BENZO[B][1,4]OXAZINE SULFONAMIDE AND RELATED COMPOUNDS FOR USE AS AGONISTS OF RORY AND THE TREATMENT OF DISEASE | UNIV MICHIGAN REGENTS (US) | 2022-04-20 | — | — | EP | disclosed |