Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 3/20 | 0.51 |
| ▸ | CPT2 | P23786 | 2/20 | 0.51 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.46 |
| ▸ | RORC | P51449 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24286419 | 0.90 | CPT1A (0.60) | CPT1ACPT2HTR6CPT1BRORC | |
| SCHEMBL24286568 | 0.83 | RORC (0.50) | RORCCYP11B1CYP11B2PKMCYP2C9 | |
| SCHEMBL24286363 | 0.83 | RORC (0.49) | CPT1ACPT2HTR6CPT1BRORC | |
| SCHEMBL24286198 | 0.82 | RORC (0.63) | CPT1ACPT2HTR6CPT1BRORC | |
| SCHEMBL24286691 | 0.82 | CPT1A (0.51) | CPT1ACPT2HTR6CPT1BRORC | |
| SCHEMBL24286447 | 0.80 | CPT1A (0.51) | CPT1ACPT2HTR6CPT1BRORC | |
| SCHEMBL24286502 | 0.79 | RORC (0.55) | RORC | |
| SCHEMBL24286256 | 0.78 | CYP3A4 (0.53) | CPT1ACPT2HTR6CPT1BRORC | |
| SCHEMBL20957213 | 0.77 | RORC (0.76) | RORC | |
| SCHEMBL20957211 | 0.77 | RORC (0.76) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3307738-B1 | ARYL DIHYDRO-2H-BENZO[B][1,4]OXAZINE SULFONAMIDE AND RELATED COMPOUNDS FOR USE AS AGONISTS OF RORY AND THE TREATMENT OF DISEASE | UNIV MICHIGAN REGENTS (US) | 2022-04-20 | — | — | EP | disclosed |