Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 5/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24286076 | 0.86 | TP53 (0.33) | PTGS2PTGS1ALDH1A1KDM4EMAPT | |
| SCHEMBL24286246 | 0.84 | GRM5 (0.35) | — | |
| SCHEMBL24286744 | 0.83 | MAP4K4 (0.36) | PTGS2MAP4K4PTGS1CYP11B1CYP11B2 | |
| SCHEMBL19725904 | 0.82 | PTGS2 (0.39) | PTGS2MAP4K4PTGS1CYP11B1CYP11B2 | |
| SCHEMBL24286075 | 0.82 | MEN1 (0.32) | CYP11B1CYP11B2MEN1KMT2A | |
| SCHEMBL17697064 | 0.81 | PTGS2 (0.35) | PTGS2CYP11B1CYP11B2KDM4E | |
| SCHEMBL24286108 | 0.78 | S1PR1 (0.31) | — | |
| SCHEMBL24286100 | 0.78 | — | — | |
| SCHEMBL17949447 | 0.77 | PDE10A (0.35) | — | |
| SCHEMBL24286101 | 0.76 | ALOX5AP (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3247712-B1 | PESTICIDALLY ACTIVE POLYCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2022-04-20 | — | — | EP | disclosed |