⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2428692 | 1.00 | — | — | |
| SCHEMBL28555134 | 0.86 | LMNA (0.43) | — | |
| SCHEMBL11656917 | 0.84 | LMNA (0.48) | — | |
| SCHEMBL4919499 | 0.84 | GABRP (0.62) | — | |
| SCHEMBL5268344 | 0.83 | GABRP (0.50) | — | |
| SCHEMBL5268348 | 0.83 | GABRP (0.50) | — | |
| Hydrochloric Acid SCHEMBL16667716 | 0.81 | GABRP (0.59) | — | |
| SCHEMBL14360308 | 0.81 | GABRP (0.59) | — | |
| SCHEMBL14360130 | 0.79 | GABRP (0.56) | — | |
| SCHEMBL2638333 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4605076-A1 | PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 3 (PNPLA3) MODIFIERS | Pfizer Inc. (US) | 2025-08-27 | — | — | EP | disclosed |
| EP-4604955-A1 | USE OF PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 3 COMPOUNDS | Pfizer Inc. (US) | 2025-08-27 | — | — | EP | disclosed |
| CN-120129681-A | Modulators of protein 3 (PNPLA 3) containing Patatin-like phospholipase domains | 辉瑞大药厂 | 2025-06-10 | — | — | CN | disclosed |
| WO-2024084363-A1 | USE OF PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 3 COMPOUNDS | PFIZER INC. (US) | 2024-04-25 | — | — | WO | disclosed |
| WO-2024084360-A1 | PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 3 (PNPLA3) MODIFIERS | PFIZER INC. (US) | 2024-04-25 | — | — | WO | disclosed |
| EP-4204397-A1 | INHIBITORS OF PSEUDOMONAS AERUGINOSA VIRULENCE FACTOR LASB | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-07-05 | — | — | EP | disclosed |
| CN-112679543-B | Lipophilic fluorescein probe and preparation method thereof | 天津全和诚科技有限责任公司 | 2022-07-22 | — | — | CN | disclosed |
| EP-3368036-B1 | MACROCYCLIC PYRIDINE-N-OXIDE DERIVATIVES AS FACTOR XIA INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2022-07-20 | — | — | EP | disclosed |
| CN-108430471-B | Factor XIa inhibitors | 默沙东公司 | 2021-07-09 | — | — | CN | disclosed |
| CN-112679543-A | Lipophilic fluorescein probe and preparation method thereof | 天津全和诚科技有限责任公司 | 2021-04-20 | — | — | CN | disclosed |
| WO-1999055726-A1 | CERTAIN THIOL INHIBITORS OF ENDOTHELIN-CONVERTING ENZYME | NOVARTIS AG (CH) | 1999-11-04 | — | — | WO | disclosed |
| WO-1999055723-A1 | CERTAIN HETEROARYL SUBSTITUTED THIOL INHIBITORS OF ENDOTHELIN-CONVERTING ENZYME | NOVARTIS AG (CH) | 1999-11-04 | — | — | WO | disclosed |
| CN-1187490-A | 5-membered ring heterocycles as inhibitors of leucocyte adhesion and as VLA-4 antagonists | HOECHST AG (DE) | 1998-07-15 | — | — | CN | disclosed |
| US-5594006-A | SUCH AS COLLEGENASE, STROMELYSIN; ANTICANCER AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-01-14 | — | — | US | disclosed |
| CN-1105799-A | Carbostyril derivatives as matrix metalloproteinases inhibitors | OTSUKA PHARMA CO LTD (JP) | 1995-07-26 | — | — | CN | disclosed |
| EP-0641323-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-03-08 | — | — | EP | disclosed |
| WO-1994021612-A1 | CARBOSTYRIL DERIVATIVES AS MATRIX METALLOPROTEINASES INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-09-29 | — | — | WO | disclosed |
| CN-1051914-A | The peptide class | MERRELL DOW PHARMA | 1991-06-05 | — | — | CN | disclosed |
| US-4021452-A | 2,5-Dihydro-2,5-dialkoxyfuran derivatives | AMERICAN CYANAMID COMPANY (US) | 1977-05-03 | — | — | US | disclosed |
| US-3952033-A | Furan intermediates and process for synthesis of 4-hydroxycyclopetenones, prostaglandin synthesis intermediates | AMERICAN CYANAMID COMPANY (US) | 1976-04-20 | — | — | US | disclosed |