Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CYBB | P04839 | 6/20 | 0.53 |
| ▸ | NOX4 | Q9NPH5 | 6/20 | 0.53 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.40 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24287567 | 0.92 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1CYBBNOX4MAOB | |
| SCHEMBL21176727 | 0.81 | ALDH1A1 (0.42) | ALDH1A1L3MBTL1CYBBNOX4MAOB | |
| SCHEMBL11823994 | 0.80 | ALDH1A1 (0.56) | ALDH1A1L3MBTL1CYBBNOX4MAOB | |
| SCHEMBL13182636 | 0.78 | ALDH1A1 (0.78) | ALDH1A1L3MBTL1CYBBNOX4KDM4E | |
| SCHEMBL25746980 | 0.77 | CYBB (0.49) | ALDH1A1L3MBTL1CYBBNOX4BACE1 | |
| SCHEMBL10010064 | 0.77 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1CYBBNOX4MAOB | |
| SCHEMBL154497 | 0.77 | ALDH1A1 (0.68) | ALDH1A1L3MBTL1CYBBNOX4MAOB | |
| SCHEMBL10010274 | 0.75 | CYBB (0.46) | ALDH1A1L3MBTL1CYBBNOX4BACE1 | |
| SCHEMBL10010271 | 0.75 | CYBB (0.46) | ALDH1A1L3MBTL1CYBBNOX4BACE1 | |
| SCHEMBL10009803 | 0.74 | ALDH1A1 (0.73) | ALDH1A1L3MBTL1MAOBKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230330067-A1 | NOVEL THIOHYDANTOIN DERIVATIVES AND USES THEREOF | CELROS BIOTECH (KR) | 2023-10-19 | — | — | US | disclosed |
| US-20230330067-A1 | NOVEL THIOHYDANTOIN DERIVATIVES AND USES THEREOF | CELROS BIOTECH (KR) | 2023-10-19 | — | — | US | disclosed |
| EP-4205740-A1 | NOVEL THIOHYDANTOIN DERIVATIVES AND USES THEREOF | Celros Biotech (KR) | 2023-07-05 | — | — | EP | disclosed |
| CN-115989060-A | Novel thiohydantoin derivatives and uses thereof | 赛罗斯生物科技 | 2023-04-18 | — | — | CN | disclosed |
| WO-2022045836-A1 | NOVEL THIOHYDANTOIN DERIVATIVES AND USES THEREOF | (주)셀로스바이오텍 | 2022-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230330067-A1 | NOVEL THIOHYDANTOIN DERIVATIVES AND USES THEREOF | NOX1, NOX4, NOX5 | ALDH1A1 477/4885L3MBTL1 3480/4885CYBB 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.