Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 11/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 10/20 | 0.35 |
| ▸ | CDK7 | P50613 | 2/20 | 0.35 |
| ▸ | CCNH | P51946 | 2/20 | 0.35 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.35 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.34 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30838031 | 0.99 | CYP11B2 (0.36) | CYP11B2CYP11B1CDK7CCNHMNAT1 | |
| SCHEMBL27095195 | 0.79 | TLR8 (0.40) | CYP11B2CYP11B1CDK7CCNHMNAT1 | |
| Hydrochloric Acid SCHEMBL30838035 | 0.78 | IDH2 (0.48) | CDK7CCNHMNAT1MAPK1SYK | |
| Hydrochloric Acid SCHEMBL30838075 | 0.78 | TLR8 (0.39) | CYP11B2CYP11B1CDK7CCNHMNAT1 | |
| SCHEMBL24288094 | 0.78 | CYP11B2 (0.41) | CYP11B2CYP11B1 | |
| Hydrochloric Acid SCHEMBL30838002 | 0.77 | IDH2 (0.50) | CDK7CCNHMNAT1 | |
| Hydrochloric Acid SCHEMBL30838016 | 0.77 | IDH2 (0.50) | CDK7CCNHMNAT1 | |
| Hydrochloric Acid SCHEMBL30838057 | 0.77 | CCNT1 (0.36) | CYP11B2CYP11B1CDK7CCNHMNAT1 | |
| Hydrochloric Acid SCHEMBL30838072 | 0.77 | CCNT1 (0.36) | CYP11B2CYP11B1CDK7CCNHMNAT1 | |
| Formic Acid SCHEMBL30838101 | 0.76 | CHEK1 (0.36) | CYP11B2CYP11B1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022053823-A1 | SUBSTITUTED PYRIMIDINE DERIVATIVES AS NICOTINIC ACETYLCHOLINESTERASE RECEPTOR ALPHA 6 MODULATOR | Cerevance, Inc. (US) | 2022-03-17 | — | — | WO | disclosed |