Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.37 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.37 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.37 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 10/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23933312 | 1.00 | ADRA2A (0.40) | ADRA2ACHRNB2ADRA2CCHRNB4CHRNA3 | |
| SCHEMBL28316817 | 0.81 | NOTUM (0.42) | ADRA2ACHRNB2ADRA2CCHRNB4CHRNA3 | |
| SCHEMBL24281814 | 0.80 | HTR2A (0.41) | CHRNB2ADRA2CCHRNB4CHRNA3CHRNA7 | |
| SCHEMBL21079081 | 0.78 | KDM1A (0.35) | KDM1A | |
| SCHEMBL21079047 | 0.77 | LMNA (0.31) | LMNACYP2C9TSHRBLMPPARA | |
| SCHEMBL21019049 | 0.77 | SLC6A4 (0.44) | ABCC9ABCC8KCNJ11KCNJ8LMNA | |
| SCHEMBL28294833 | 0.74 | KDM1A (0.43) | ADRA2ACHRNB2ADRA2CCHRNB4CHRNA3 | |
| SCHEMBL18161909 | 0.74 | KDM1A (0.43) | ADRA2ACHRNB2ADRA2CCHRNB4CHRNA3 | |
| SCHEMBL28294840 | 0.74 | KDM1A (0.51) | ADRA2ACHRNB2ADRA2CCHRNB4CHRNA3 | |
| SCHEMBL28645067 | 0.73 | ADRA2A (0.43) | ADRA2ACHRNB2ADRA2CCHRNB4CHRNA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3964495-A1 | MOLECULES HAVING PESTICIDAL UTILITY, AND COMPOSITIONS, AND PROCESSES, RELATED THERETO | Dow AgroSciences LLC (US) | 2022-03-09 | — | — | EP | disclosed |