Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 2/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24291092 | 0.82 | BACE1 (0.44) | PABPC1HTTBACE1CYP1A2CYP2C19 | |
| SCHEMBL24289138 | 0.81 | ALDH1A1 (0.47) | — | |
| SCHEMBL24292074 | 0.77 | ABL1 (0.33) | PABPC1 | |
| SCHEMBL2621767 | 0.75 | CSF1R (0.42) | TGFBR1PABPC1HTTTSHRBACE1 | |
| SCHEMBL15447229 | 0.75 | HTT (0.46) | TGFBR1HTTTSHRCYP1A2CYP2C19 | |
| SCHEMBL24289041 | 0.73 | TSHR (0.35) | HTTTSHRCYP2C19 | |
| SCHEMBL21254680 | 0.70 | TGFBR1 (0.33) | TGFBR1HTTTSHRCYP1A2CYP2C19 | |
| SCHEMBL13905406 | 0.70 | ALDH1A1 (0.61) | HTT | |
| SCHEMBL24291030 | 0.69 | — | — | |
| SCHEMBL24289934 | 0.69 | DPP4 (0.32) | PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022073469-A1 | COMPOUNDS AND METHODS OF TREATING CANCERS | CULLGEN (SHANGHAI) , INC. (CN) | 2022-04-14 | — | — | WO | disclosed |