Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27933593 | 0.92 | FAAH (0.40) | FAAHMGLLNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28949648 | 0.92 | NPC1 (0.42) | FAAHMGLLNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31081840 | 0.85 | FAAH (0.43) | FAAHMGLLNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL31081780 | 0.81 | FAAH (0.46) | FAAHMGLLSIGMAR1 | |
| SCHEMBL31081832 | 0.81 | FAAH (0.46) | FAAHMGLLSIGMAR1 | |
| SCHEMBL31389482 | 0.79 | NPC1 (0.37) | FAAHMGLLNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27091113 | 0.75 | NPC1 (0.38) | FAAHMGLLNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24290453 | 0.75 | NPC1 (0.38) | FAAHMGLLNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27092020 | 0.75 | NPC1 (0.35) | FAAHMGLLNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27091203 | 0.75 | NPC1 (0.35) | FAAHMGLLNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022073469-A1 | COMPOUNDS AND METHODS OF TREATING CANCERS | CULLGEN (SHANGHAI) , INC. (CN) | 2022-04-14 | — | — | WO | disclosed |