Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24290451 | 0.92 | FAAH (0.41) | FAAHMGLLSIGMAR1NPC1RAB9A | |
| SCHEMBL28949648 | 0.84 | NPC1 (0.42) | FAAHMGLLSIGMAR1NPC1RAB9A | |
| SCHEMBL31081840 | 0.82 | FAAH (0.43) | FAAHMGLLSIGMAR1NPC1RAB9A | |
| SCHEMBL31081780 | 0.78 | FAAH (0.46) | FAAHMGLLSIGMAR1 | |
| SCHEMBL31081832 | 0.78 | FAAH (0.46) | FAAHMGLLSIGMAR1 | |
| SCHEMBL4956106 | 0.74 | NPC1 (0.38) | FAAHMGLLNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10049902 | 0.73 | SIGMAR1 (0.41) | SIGMAR1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL18007582 | 0.73 | SIGMAR1 (0.41) | SIGMAR1RAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL17012837 | 0.73 | SIGMAR1 (0.41) | SIGMAR1SMN1; SMN2ALDH1A1SLC18A3WDR5 | |
| SCHEMBL9383085 | 0.73 | DDB1 (0.45) | MGLLNPC1RAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103261196-A | Pyrazolopyridines as inhibitors of the kinase lrrk2 | MEDICAL RES COUNCIL TECHNOLOGY | 2013-08-21 | — | — | CN | disclosed |