SCHEMBL24293188

SCHEMBL24293188

CC1(C)c2ccccc2C2(c3ccccc3Oc3cccc(-c4cccc(-c5cc(-c6ccc(-c7ccccc7)c7ccccc67)nc(-c6ccccc6)n5)c4)c32)c2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.32
MEN1 O00255 2/20 0.32
ALDH1A1 P00352 2/20 0.32
LMNA P02545 2/20 0.32
MAPT P10636 2/20 0.32
HPGD P15428 2/20 0.32
KMT2A Q03164 2/20 0.32
GLA P06280 1/20 0.32
PTPN1 P18031 1/20 0.31
ADORA2A P29274 1/20 0.31
ADORA1 P30542 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24293185 0.90 PTPN1 (0.32) KDM4EALDH1A1MAPTHPGDPTPN1
SCHEMBL24905185 0.89
SCHEMBL23814597 0.89 MAPT (0.35) KDM4EMEN1ALDH1A1LMNAMAPT
SCHEMBL24293335 0.88 MEN1 (0.35) KDM4EMEN1ALDH1A1LMNAMAPT
SCHEMBL24293732 0.88 ADORA2A (0.35) KDM4EMEN1ALDH1A1LMNAMAPT
SCHEMBL24293825 0.86 MEN1 (0.34) KDM4EMEN1ALDH1A1LMNAMAPT
SCHEMBL24293256 0.85 THRB (0.32) KDM4EMEN1ALDH1A1LMNAMAPT
SCHEMBL24293233 0.85 MEN1 (0.33) KDM4EMEN1ALDH1A1LMNAMAPT
SCHEMBL24293253 0.84 ALDH1A1 (0.36) KDM4EMEN1ALDH1A1LMNAMAPT
SCHEMBL24293358 0.84 ALDH1A1 (0.38) KDM4EMEN1ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220376178-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2022-11-24 US disclosed
US-20220123218-A1 ORGANIC ELECTROLUMINESCENT DEVICE LG CHEM, LTD. (KR) 2022-04-21 US disclosed