SCHEMBL2429358

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12329094	1.00	KMT2A (0.43)	KMT2ASMN1; SMN2ANO1MAPTCYP2C19
	SCHEMBL2430451	1.00	KMT2A (0.43)	KMT2ASMN1; SMN2ANO1MAPTCYP2C19
	SCHEMBL4341753	0.92	KMT2A (0.42)	KMT2ASMN1; SMN2MAPTCYP2C19NPC1
	SCHEMBL4341749	0.92	KMT2A (0.42)	KMT2ASMN1; SMN2MAPTCYP2C19NPC1
	SCHEMBL2430826	0.91	SMN1; SMN2 (0.42)	KMT2ASMN1; SMN2P2RY14NPC1RAB9A
	SCHEMBL2432741	0.91	RAB9A (0.42)	KMT2ASMN1; SMN2NPC1RAB9AALDH1A1
	SCHEMBL2432736	0.91	RAB9A (0.42)	KMT2ASMN1; SMN2NPC1RAB9AALDH1A1
	SCHEMBL2430828	0.91	SMN1; SMN2 (0.42)	KMT2ASMN1; SMN2P2RY14NPC1RAB9A
	SCHEMBL2428231	0.89	CDK9 (0.33)	KMT2ASMN1; SMN2NPC1RAB9AALDH1A1
	SCHEMBL2431844	0.89	CDK9 (0.33)	KMT2ASMN1; SMN2NPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.