Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 15/20 | 0.38 |
| ▸ | EGFR | P00533 | 3/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | ABL2 | P42684 | 2/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24293646 | 0.89 | SRC (0.47) | ADKSRCEGFRABL1ABL2 | |
| SCHEMBL24293871 | 0.77 | METTL3 (0.40) | ADKSRCEGFR | |
| SCHEMBL357171 | 0.76 | SRC (0.52) | ADKSRCEGFRABL1ABL2 | |
| SCHEMBL868904 | 0.76 | SRC (0.48) | ADKSRCEGFRABL1ABL2 | |
| SCHEMBL14635891 | 0.75 | SRC (0.53) | ADKSRCEGFRABL1ABL2 | |
| SCHEMBL15914127 | 0.75 | SRC (0.53) | ADKSRCEGFRABL1ABL2 | |
| SCHEMBL25047438 | 0.74 | ADK (0.42) | ADKSRCEGFRABL1ABL2 | |
| SCHEMBL24293887 | 0.73 | RIPK2 (0.39) | ADKSRCEGFRABL1ABL2 | |
| SCHEMBL18640950 | 0.73 | ADK (0.54) | ADKSRCEGFRABL1ABL2 | |
| SCHEMBL25048063 | 0.70 | SRC (0.40) | ADKSRCEGFRABL1ABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022074391-A1 | COMPOUNDS INHIBITORS OF METTL3 | STORM THERAPEUTICS LIMITED (GB) | 2022-04-14 | — | — | WO | disclosed |