Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 19/20 | 0.77 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29478283 | 0.87 | METTL3 (1.00) | METTL3 | |
| SCHEMBL27178365 | 0.87 | METTL3 (1.00) | METTL3 | |
| SCHEMBL29478258 | 0.84 | METTL3 (1.00) | METTL3 | |
| SCHEMBL19412759 | 0.78 | METTL3 (0.59) | METTL3PRMT5 | |
| SCHEMBL29478263 | 0.77 | METTL3 (1.00) | METTL3 | |
| SCHEMBL27178419 | 0.77 | METTL3 (1.00) | METTL3 | |
| SCHEMBL24293511 | 0.71 | METTL3 (0.69) | METTL3 | |
| SCHEMBL24293508 | 0.71 | METTL3 (0.69) | METTL3 | |
| SCHEMBL24293886 | 0.71 | METTL3 (1.00) | METTL3 | |
| SCHEMBL29478273 | 0.71 | METTL3 (0.90) | METTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022074391-A1 | COMPOUNDS INHIBITORS OF METTL3 | STORM THERAPEUTICS LIMITED (GB) | 2022-04-14 | — | — | WO | disclosed |