Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METTL3 | Q86U44 | 14/20 | 0.59 |
| ▸ | ADK | P55263 | 4/20 | 0.52 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.51 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17131316 | 0.87 | ADK (0.52) | METTL3ADKPRMT5RAPGEF3 | |
| SCHEMBL19412718 | 0.87 | METTL3 (0.51) | METTL3ADKPRMT5 | |
| SCHEMBL17106776 | 0.81 | PRMT5 (0.59) | METTL3ADKPRMT5 | |
| SCHEMBL20419182 | 0.81 | PRMT5 (0.59) | METTL3ADKPRMT5 | |
| SCHEMBL24313576 | 0.81 | PRMT5 (0.59) | METTL3ADKPRMT5 | |
| SCHEMBL17106708 | 0.81 | METTL3 (0.45) | METTL3ADKPRMT5RAPGEF3 | |
| SCHEMBL8653483 | 0.78 | AHCY (0.65) | — | |
| SCHEMBL24294014 | 0.78 | METTL3 (0.77) | METTL3PRMT5 | |
| SCHEMBL19412712 | 0.77 | PRMT5 (0.49) | METTL3ADKPRMT5RAPGEF3 | |
| SCHEMBL6062467 | 0.76 | POLB (0.56) | METTL3PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9777035-B2 | 4′-substituted nucleoside reverse transcriptase inhibitors | MERCK SHARP & DOHME CORP. (US) | 2017-10-03 | — | — | US | disclosed |