Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAO1 | P09471 | 6/20 | 0.41 |
| ▸ | GUSB | P08236 | 2/20 | 0.41 |
| ▸ | EBP | Q15125 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | GLB1 | P16278 | 1/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 5/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.36 |
| ▸ | GBA1 | P04062 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25653939 | 0.85 | GLB1 (0.52) | GNAO1GUSBEBPSIGMAR1GLB1 | |
| SCHEMBL7569033 | 0.82 | — | — | |
| SCHEMBL21011949 | 0.80 | ALDH1A1 (0.44) | GNAO1GUSBGLB1GBA1 | |
| SCHEMBL10642680 | 0.76 | — | — | |
| SCHEMBL18290251 | 0.74 | GLB1 (0.54) | GNAO1GUSBEBPSIGMAR1GLB1 | |
| SCHEMBL6400664 | 0.74 | CYP1A2 (0.39) | GUSBGLB1GBA1 | |
| SCHEMBL19245845 | 0.74 | GBA1 (0.47) | GUSBEBPSIGMAR1GLB1GBA1 | |
| SCHEMBL9830506 | 0.72 | ALDH1A1 (0.41) | GNAO1GUSBGLB1GNAI3GNAI1 | |
| SCHEMBL18497449 | 0.71 | HRH3 (0.46) | GNAO1SIGMAR1 | |
| SCHEMBL11540777 | 0.71 | GNAO1 (0.42) | GNAO1GUSBGLB1GNAI3GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3971176-A1 | AROMATIC AMINE AR AND BET TARGETING PROTEIN DEGRADATION CHIMERA COMPOUND AND USE | Hinova Pharmaceuticals Inc. (CN) | 2022-03-23 | — | — | EP | disclosed |