Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MOGAT2 | Q3SYC2 | 2/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.43 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.43 |
| ▸ | CASR | P41180 | 3/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.39 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22296950 | 0.86 | HRH4 (0.52) | MCHR1HRH4CARM1PRMT6 | |
| SCHEMBL23844192 | 0.80 | MCHR1 (0.48) | MCHR1CARM1PRMT6 | |
| SCHEMBL25124463 | 0.79 | MOGAT2 (0.51) | MOGAT2MCHR1USP28USP25HRH4 | |
| SCHEMBL13785068 | 0.77 | HDAC1 (0.44) | MOGAT2MCHR1USP28USP25HRH4 | |
| SCHEMBL26748715 | 0.76 | MOGAT2 (0.47) | MOGAT2AKT1 | |
| SCHEMBL26748714 | 0.76 | MOGAT2 (0.47) | MOGAT2AKT1 | |
| SCHEMBL22526350 | 0.75 | RORC (0.45) | MCHR1 | |
| SCHEMBL8251557 | 0.74 | RORC (0.56) | MCHR1USP28 | |
| SCHEMBL4333368 | 0.74 | MAPT (0.52) | — | |
| SCHEMBL8729299 | 0.74 | SMN1; SMN2 (0.40) | USP28USP25 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3971176-A1 | AROMATIC AMINE AR AND BET TARGETING PROTEIN DEGRADATION CHIMERA COMPOUND AND USE | Hinova Pharmaceuticals Inc. (CN) | 2022-03-23 | — | — | EP | disclosed |