SCHEMBL24295253

SCHEMBL24295253

c1ccc2oc(-c3ccc(Oc4ccc(-c5nc6ccccc6o5)cc4)cc3)nc2c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.67
RAB9A P51151 4/20 0.67
MEN1 O00255 2/20 0.67
KMT2A Q03164 2/20 0.67
ATM Q13315 1/20 0.67
HSD17B10 Q99714 4/20 0.61
ALDH1A1 P00352 3/20 0.61
KDM4E B2RXH2 2/20 0.61
HPGD P15428 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
TP53 P04637 1/20 0.61
MMP2 P08253 1/20 0.58
MMP9 P14780 1/20 0.58
MMP8 P22894 1/20 0.58
MMP13 P45452 1/20 0.58
MAPT P10636 1/20 0.57
CHRNB4 P30926 1/20 0.57
CHRNA3 P32297 1/20 0.57
CHRNA7 P36544 1/20 0.57
CHRNA10 Q9GZZ6 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9114869 0.97 NPC1 (0.63) NPC1RAB9AMEN1KMT2AATM
SCHEMBL10047629 0.91 PTPN2 (0.62) NPC1RAB9AMEN1KMT2AATM
SCHEMBL13067562 0.91 NPC1 (0.60) NPC1RAB9AMEN1KMT2AATM
SCHEMBL31170 0.89 NPC1 (0.81) NPC1RAB9AMEN1KMT2AATM
SCHEMBL10047616 0.87 NPC1 (0.59) NPC1RAB9AMEN1KMT2AATM
Methane SCHEMBL29265168 0.87 NPC1 (0.79) NPC1RAB9AMEN1KMT2AATM
SCHEMBL31476 0.87 NPC1 (0.79) NPC1RAB9AMEN1KMT2AATM
SCHEMBL3365960 0.86 NPC1 (0.63) NPC1RAB9AMEN1KMT2AATM
SCHEMBL1199992 0.86 PTPN2 (0.68) NPC1RAB9AMEN1KMT2AATM
SCHEMBL13049179 0.86 NPC1 (0.63) NPC1RAB9AMEN1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12018128-B2 Particle-dispersed polyimide precursor solution, method for producing porous polyimide film, and porous polyimide film FUJIFILM BUSINESS INNOVATION CORP. (JP) 2024-06-25 US disclosed
US-20220119596-A1 PARTICLE-DISPERSED POLYIMIDE PRECURSOR SOLUTION, METHOD FOR PRODUCING POROUS POLYIMIDE FILM, AND POROUS POLYIMIDE FILM FUJIFILM BUSINESS INNOVATION CORP. (JP) 2022-04-21 US disclosed