SCHEMBL31476

SCHEMBL31476

c1ccc2oc(-c3ccc(-c4ccc(-c5nc6ccccc6o5)cc4)cc3)nc2c1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 9/20 0.79
RAB9A P51151 7/20 0.79
MEN1 O00255 4/20 0.79
KMT2A Q03164 4/20 0.79
ATM Q13315 1/20 0.79
HSD17B10 Q99714 6/20 0.71
ALDH1A1 P00352 6/20 0.71
HPGD P15428 6/20 0.71
KDM4E B2RXH2 4/20 0.71
SMN1; SMN2 Q16637 4/20 0.71
TP53 P04637 4/20 0.71
MMP2 P08253 1/20 0.67
MMP9 P14780 1/20 0.67
MMP8 P22894 1/20 0.67
MMP13 P45452 1/20 0.67
MAPT P10636 3/20 0.61
HCRTR1 O43613 1/20 0.58
PKM P14618 1/20 0.58
CYP1A2 P05177 1/20 0.58
CYP2C9 P11712 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31170 0.98 NPC1 (0.81) NPC1RAB9AMEN1KMT2AATM
SCHEMBL27281692 0.96 NPC1 (0.73) NPC1RAB9AMEN1KMT2AATM
SCHEMBL752483 0.96 NPC1 (0.73) NPC1RAB9AMEN1KMT2AATM
Methane SCHEMBL29265168 0.96 NPC1 (0.79) NPC1RAB9AMEN1KMT2AATM
SCHEMBL21674168 0.94 NPC1 (0.71) NPC1RAB9AMEN1KMT2AATM
SCHEMBL21674267 0.92 NPC1 (0.69) NPC1RAB9AMEN1KMT2AATM
SCHEMBL13067542 0.92 NPC1 (0.69) NPC1RAB9AMEN1KMT2AATM
2-Phenylbenzo[D]Oxazole SCHEMBL29767802 0.91 NPC1 (0.72) NPC1RAB9AMEN1KMT2AATM
2-Phenylbenzo[D]Oxazole SCHEMBL31738605 0.91 NPC1 (0.72) NPC1RAB9AMEN1KMT2AATM
2-Phenylbenzo[D]Oxazole SCHEMBL29819732 0.91 NPC1 (0.72) NPC1RAB9AMEN1KMT2AATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5142343-A An electroluminiscent oligomer semiconductor zone and an insulator zone containing a light-emitting zone sandwiched between electrodes IDEMITSU KOSAN CO., LTD. (JP) 1992-08-25 US claimed
EP-0120673-B1 ORGANIC ELECTROLUMINESCENT DEVICES HAVING IMPROVED POWER CONVERSION EFFICIENCIES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-06-01 EP claimed
US-4539507-A CHARGE TRANSFER COMPOUNDS EASTMAN KODAK COMPANY (US) 1985-09-03 US claimed
EP-0120673-A2 Organic electroluminescent devices having improved power conversion efficiencies EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-10-03 EP claimed
US-6423429-B1 None US disclosed
US-12018128-B2 Particle-dispersed polyimide precursor solution, method for producing porous polyimide film, and porous polyimide film FUJIFILM BUSINESS INNOVATION CORP. (JP) 2024-06-25 US disclosed
US-11362283-B2 Organic electroluminescent element LG CHEM, LTD. 2022-06-14 US disclosed
US-20220119596-A1 PARTICLE-DISPERSED POLYIMIDE PRECURSOR SOLUTION, METHOD FOR PRODUCING POROUS POLYIMIDE FILM, AND POROUS POLYIMIDE FILM FUJIFILM BUSINESS INNOVATION CORP. (JP) 2022-04-21 US disclosed
CN-113512055-A Silane derivative, light-emitting device material and light-emitting device 浙江华显光电科技有限公司 2021-10-19 CN disclosed
US-10281110-B2 Backlit, laser engraved metalized promotional items Amsterdam Printing & Litho, Inc. (US) 2019-05-07 US disclosed
US-10283568-B2 Light emitting apparatus having first luminous body and second luminous body PIONEER CORPORATION (JP) 2019-05-07 US disclosed
US-20180259152-A1 BACKLIT, LASER ENGRAVED METALIZED PROMOTIONAL ITEMS Amsterdam Printing & Litho, Inc. 2018-09-13 US disclosed
EP-0563811-A1 Silanamine derivative and process for the production thereof, and organical EL device using the said silanamine derivative IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-10-06 EP disclosed
EP-0548366-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-06-30 EP disclosed
US-5142343-A An electroluminiscent oligomer semiconductor zone and an insulator zone containing a light-emitting zone sandwiched between electrodes IDEMITSU KOSAN CO., LTD. (JP) 1992-08-25 US disclosed
US-5077142-A Electroluminescent devices RICOH COMPANY, LTD. (JP) 1991-12-31 US disclosed
EP-0439627-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-08-07 EP disclosed
EP-0120673-B1 ORGANIC ELECTROLUMINESCENT DEVICES HAVING IMPROVED POWER CONVERSION EFFICIENCIES EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-06-01 EP disclosed
US-4539507-A CHARGE TRANSFER COMPOUNDS EASTMAN KODAK COMPANY (US) 1985-09-03 US disclosed
EP-0120673-A2 Organic electroluminescent devices having improved power conversion efficiencies EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-10-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11362283-B2 Organic electroluminescent element NCS1, POU5F1, POU2F1 NPC1 3366/4885RAB9A 1656/4885MEN1 1781/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.