SCHEMBL1199992

SCHEMBL1199992

COc1ccc(-c2nc3ccccc3o2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN2 P17706 2/20 0.68
PTPN1 P18031 2/20 0.68
PTPN5 P54829 2/20 0.68
NPC1 O15118 10/20 0.66
RAB9A P51151 8/20 0.64
ALDH1A1 P00352 6/20 0.64
MAPT P10636 6/20 0.64
KDM4E B2RXH2 5/20 0.64
SMN1; SMN2 Q16637 5/20 0.64
LMNA P02545 2/20 0.64
MEN1 O00255 2/20 0.63
KMT2A Q03164 2/20 0.63
ATM Q13315 1/20 0.63
HPGD P15428 4/20 0.62
HSD17B10 Q99714 3/20 0.62
USP2 O75604 1/20 0.60
GAA P10253 1/20 0.60
TSHR P16473 1/20 0.60
STAT3 P40763 1/20 0.60
TP53 P04637 3/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10047629 0.94 PTPN2 (0.62) PTPN2PTPN1PTPN5NPC1RAB9A
SCHEMBL11337898 0.87 MAPT (0.74) PTPN2PTPN1PTPN5NPC1RAB9A
SCHEMBL24295253 0.86 NPC1 (0.67) PTPN2PTPN1PTPN5NPC1RAB9A
SCHEMBL31170 0.86 NPC1 (0.81) PTPN2PTPN1PTPN5NPC1RAB9A
Methane SCHEMBL29265168 0.84 NPC1 (0.79) PTPN2PTPN1PTPN5NPC1RAB9A
SCHEMBL31476 0.84 NPC1 (0.79) PTPN2PTPN1PTPN5NPC1RAB9A
SCHEMBL9114869 0.83 NPC1 (0.63) PTPN2PTPN1PTPN5NPC1RAB9A
SCHEMBL13049179 0.83 NPC1 (0.63) PTPN2PTPN1PTPN5NPC1RAB9A
SCHEMBL3365960 0.83 NPC1 (0.63) PTPN2PTPN1PTPN5NPC1RAB9A
SCHEMBL12639220 0.83 NPC1 (0.68) PTPN2PTPN1PTPN5NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012108689-A2 NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREFOR 부산대학교 산학협력단 (KR) 2012-08-16 WO claimed
US-20230038825-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM, PATTERN FORMING METHOD, METHOD FOR MANUFACTURING ELECTRONIC DEVICE, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION FOR MANUFACTURING PHOTOMASK, AND METHOD FOR MANUFACTURING PHOTOMASK FUJIFILM CORPORATION (JP) 2023-02-09 US disclosed
WO-2023008346-A1 ACTINIC-RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC-RAY-SENSITIVE OR RADIATION-SENSITIVE FILM, METHOD FOR FORMING PATTERN, AND METHOD FOR PRODUCING ELECTRONIC DEVICE 富士フイルム株式会社 2023-02-02 WO disclosed
CN-109265409-B Synthesis method of 2-substituted benzoxazole, 2-substituted benzothiazole and derivatives thereof 重庆医科大学 2022-09-02 CN disclosed
US-20220206386-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2022-06-30 US disclosed
CN-112250779-B Photochromic microspheres, preparation method and application 深圳市裕同包装科技股份有限公司 2022-06-10 CN disclosed
US-20210165325-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM, PATTERN FORMING METHOD, METHOD FOR MANUFACTURING ELECTRONIC DEVICE, AND COMPOUND FUJIFILM CORPORATION (JP) 2021-06-03 US disclosed
WO-2021065450-A1 ACTIVE LIGHT SENSITIVE OR RADIATION SENSITIVE RESIN COMPOSITION, ACTIVE LIGHT SENSITIVE OR RADIATION SENSITIVE FILM, PATTERN FORMING METHOD, AND METHOD FOR PRODUCING ELECTRONIC DEVICE 富士フイルム株式会社 2021-04-08 WO disclosed
US-20200183279-A1 PHOTOSENSITIVE RESIN COMPOSITION, RESIST FILM, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE FUJI FILM CORPORATION (JP) 2020-06-11 US disclosed
WO-2020045534-A1 ACTIVE-LIGHT-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTIVE-LIGHT-SENSITIVE OR RADIATION-SENSITIVE FILM, PATTERN FORMATION METHOD, METHOD FOR MANUFACTURING ELECTRONIC DEVICE, AND COMPOUND 富士フイルム株式会社 2020-03-05 WO disclosed
EP-1521798-A1 SUNSCREENS DSM IP Assets B.V. (NL) 2005-04-13 EP disclosed
US-20040242615-A1 Utilities of olefin derivatives SHIONOGI & CO., LTD. (JP) 2004-12-02 US disclosed
WO-2004007592-A1 SUNSCREENS DSM IP ASSETS B.V. (NL) 2004-01-22 WO disclosed
EP-0623115-A4 NUCLEOPHILIC DISPLACEMENT METHOD FOR SYNTHESIS OF NON-RIGID PBZ POLYMERS. DOW CHEMICAL CO (US) 1995-01-11 EP disclosed
EP-0623115-A1 NUCLEOPHILIC DISPLACEMENT METHOD FOR SYNTHESIS OF NON-RIGID PBZ POLYMERS THE DOW CHEMICAL COMPANY (US) 1994-11-09 EP disclosed
WO-1993014071-A1 NUCLEOPHILIC DISPLACEMENT METHOD FOR SYNTHESIS OF NON-RIGID PBZ POLYMERS THE DOW CHEMICAL COMPANY (US) 1993-07-22 WO disclosed
US-5216110-A Monomers useful in nucleophilic displacement synthesis of polybenzazole polymers THE DOW CHEMICAL COMPANY (US) 1993-06-01 US disclosed
US-5194562-A Nucleophilic displacement method for synthesis of non-rigid PBZ polymers THE DOW CHEMICAL COMPANY (US) 1993-03-16 US disclosed
US-5104960-A Nucleophilic displacement method for synthesis of non-rigid PBZ polymers THE DOW CHEMICAL COMPANY (US) 1992-04-14 US disclosed
EP-0479161-A1 Synthesis of heterocyclic compounds EASTMAN CHEMICAL COMPANY (US) 1992-04-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040242615-A1 Utilities of olefin derivatives APOL1, NR1H2, APOB PTPN2 2694/4885PTPN1 2551/4885PTPN5 3015/4885
US-20200183279-A1 PHOTOSENSITIVE RESIN COMPOSITION, RESIST FILM, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE EED, RER1, CFD PTPN2 4083/4885PTPN1 4149/4885PTPN5 4201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.