SCHEMBL24296252

SCHEMBL24296252

C1=Cc2ccc(-c3ccc(Nc4ccc5c(c4)c4ccccc4n5-c4ccc5ccccc5c4)cc3)cc2CC1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
DHFR P00374 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18088907 0.89 HTR3A (0.31)
SCHEMBL22476135 0.86 KDM4E (0.33)
SCHEMBL20356450 0.81 KDM4E (0.37)
SCHEMBL14580818 0.81 ALDH1A1 (0.46) ALDH1A1CYP3A4HPGDHSD17B10DHFR
SCHEMBL18516338 0.81 KDM4E (0.43)
SCHEMBL25535540 0.80 PTGDR2 (0.32)
SCHEMBL30567038 0.79 ALDH1A1 (0.43) ALDH1A1CYP3A4HPGDHSD17B10
SCHEMBL26110989 0.79 ALDH1A1 (0.43) ALDH1A1CYP3A4HPGDHSD17B10
SCHEMBL23228102 0.78 KDM4E (0.43)
SCHEMBL14580814 0.78 ALDH1A1 (0.54) ALDH1A1CYP3A4HPGDHSD17B10DHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022045743-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2022-03-03 WO disclosed