Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14011423 | 1.00 | ALDH1A1 (0.47) | ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL12848699 | 0.97 | ALDH1A1 (0.44) | ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL20078810 | 0.97 | ALDH1A1 (0.44) | ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL25146996 | 0.97 | ALDH1A1 (0.44) | ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL20663106 | 0.94 | ALDH1A1 (0.47) | ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL24226852 | 0.92 | ALDH1A1 (0.37) | ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL12689882 | 0.92 | ALDH1A1 (0.44) | ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL23330446 | 0.92 | ALDH1A1 (0.37) | ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL22812407 | 0.92 | ALDH1A1 (0.37) | ALDH1A1THRBMEN1KMT2A | |
| SCHEMBL23568304 | 0.92 | ALDH1A1 (0.37) | ALDH1A1THRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220119366-A1 | TETRAZOLE CONTAINING APOPTOSIS SIGNAL-REGULATING KINASE 1 INHIBITORS AND METHODS OF USE THEREOF | ENANTA PHARM INC (US) | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119366-A1 | TETRAZOLE CONTAINING APOPTOSIS SIGNAL-REGULATING KINASE 1 INHIBITORS AND METHODS OF USE THEREOF | AIFM1, BAD, IRAK1 | ALDH1A1 1233/4885THRB 1258/4885MEN1 4327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.