Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSL1 | P33121 | 11/20 | 0.46 |
| ▸ | ACSL3 | O95573 | 1/20 | 0.46 |
| ▸ | ACSL6 | Q9UKU0 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24299375 | 1.00 | ACSL1 (0.46) | ACSL1ACSL3ACSL6PGRNPC1 | |
| SCHEMBL28567534 | 0.87 | PGR (0.48) | PGRNPC1RAB9AARFFAR4 | |
| SCHEMBL20046474 | 0.84 | PGR (0.60) | ACSL1ACSL3ACSL6PGRAR | |
| SCHEMBL24298723 | 0.84 | PGR (0.60) | ACSL1ACSL3ACSL6PGRAR | |
| SCHEMBL24298603 | 0.84 | ACSL1 (0.46) | ACSL1ACSL3ACSL6PGRDGAT1 | |
| SCHEMBL24298588 | 0.84 | PGR (0.60) | ACSL1ACSL3ACSL6PGRAR | |
| SCHEMBL24299380 | 0.84 | ACSL1 (0.46) | ACSL1ACSL3ACSL6PGRDGAT1 | |
| SCHEMBL19641648 | 0.82 | PGR (0.43) | PGRARFFAR4ACACB | |
| SCHEMBL22557802 | 0.81 | PGR (0.43) | PGRARFFAR4ACACB | |
| SCHEMBL22557803 | 0.81 | PGR (0.43) | PGRARFFAR4ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022048605-A1 | HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, INTERMEDIATE, COMPOSITION, AND APPLICATIONS | 南昌奥瑞药业有限公司 | 2022-03-10 | — | — | WO | disclosed |