SCHEMBL24299463

SCHEMBL24299463

CC(C)/C=C/c1ccc(-c2ccc(/C=C/C(C)C)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.37
CYP2C9 P11712 3/20 0.37
CYP2C19 P33261 3/20 0.37
MAPT P10636 2/20 0.37
ALDH1A1 P00352 2/20 0.37
ALOX15 P16050 1/20 0.37
HDAC2 Q92769 3/20 0.36
HDAC8 Q9BY41 2/20 0.36
HDAC6 Q9UBN7 2/20 0.36
HDAC3 O15379 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC1 Q13547 1/20 0.36
HDAC7 Q8WUI4 1/20 0.36
HDAC10 Q969S8 1/20 0.36
HDAC11 Q96DB2 1/20 0.36
HDAC9 Q9UKV0 1/20 0.36
HDAC5 Q9UQL6 1/20 0.36
CA1 P00915 1/20 0.35
MGLL Q99685 1/20 0.35
MEN1 O00255 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11800306 0.82 CYP3A4 (0.53) CYP3A4CYP2C9CYP2C19MAPTCA1
SCHEMBL11800299 0.82 CYP3A4 (0.53) CYP3A4CYP2C9CYP2C19MAPTCA1
SCHEMBL2869906 0.80 NFE2L2 (0.54) MEN1KMT2ALMNATRPA1
SCHEMBL105258 0.80 NFE2L2 (0.54) MEN1KMT2ALMNATRPA1
SCHEMBL18714866 0.80 APP (0.52) CYP3A4CYP2C9CYP2C19MAPTALDH1A1
SCHEMBL23623944 0.80 TYR (0.54) CYP2C9MAPTALDH1A1MEN1KMT2A
SCHEMBL9967765 0.80 APP (0.48) CYP3A4CYP2C9CYP2C19MAPTALDH1A1
SCHEMBL14465008 0.80 AHR (0.48) CYP1A2
SCHEMBL9967711 0.80 AHR (0.48) CYP1A2
SCHEMBL29078901 0.80 ALDH1A1 (0.52) CYP3A4CYP2C9CYP2C19MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220105001-A1 COMPOSITIONS AND DEVICES FOR CONTAINING MEDICAL FLUIDS ICU MEDICAL, INC. 2022-04-07 US disclosed