SCHEMBL24299501

SCHEMBL24299501

Cn1c2cnccc2c2ccc(-c3cc4c(cn3)c3ccccc3n4C)cc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
POLB P06746 1/20 0.44
GAA P10253 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
TOP2A P11388 1/20 0.43
ROCK2 O75116 4/20 0.42
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
GPR3 P46089 1/20 0.41
KIF11 P52732 1/20 0.40
CYP11B2 P19099 2/20 0.39
MAOA P21397 4/20 0.39
MAOB P27338 4/20 0.39
ACHE P22303 1/20 0.39
ADORA3 P0DMS8 1/20 0.38
ADORA2A P29274 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19731916 0.94 TOP2A (0.42) NPC1RAB9APOLBGAARXFP1
SCHEMBL23306901 0.88 TOP2A (0.39) NPC1RAB9APOLBGAARXFP1
SCHEMBL22883537 0.87 TOP2A (0.46) NPC1RAB9APOLBGAARXFP1
SCHEMBL23371968 0.82 ROCK2 (0.46) NPC1RAB9APOLBGAARXFP1
SCHEMBL24436980 0.82 TOP2A (0.38) NPC1RAB9APOLBGAARXFP1
SCHEMBL280032 0.80 GPR3 (0.64) TOP2AROCK2GPR3KIF11CYP11B2
SCHEMBL30929605 0.80 GPR3 (0.64) TOP2AROCK2GPR3KIF11CYP11B2
SCHEMBL29358773 0.80 GPR3 (0.64) TOP2AROCK2GPR3KIF11CYP11B2
SCHEMBL18381764 0.79 GPR3 (0.61) TOP2AROCK2GPR3KIF11CYP11B2
Hydrochloric Acid SCHEMBL3333705 0.79 GPR3 (0.61) TOP2AROCK2GPR3KIF11CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11812660-B2 Organic compound, electroluminescent material and application thereof WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2023-11-07 US disclosed
US-20220123226-A1 ORGANIC COMPOUND, ELECTROLUMINESCENT MATERIAL AND APPLICATION THEREOF WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2022-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220123226-A1 ORGANIC COMPOUND, ELECTROLUMINESCENT MATERIAL AND APPLICATION THEREOF MRPS22, RPS3A, MRPS23 NPC1 3028/4885RAB9A 1696/4885POLB 4406/4885
US-11812660-B2 Organic compound, electroluminescent material and application thereof MRPS22, RPS3A, MRPS23 NPC1 3028/4885RAB9A 1696/4885POLB 4406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.