Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.54 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.49 |
| ▸ | TACR1 | P25103 | 3/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | EDNRA | P25101 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | ECE1 | P42892 | 2/20 | 0.47 |
| ▸ | GHSR | Q92847 | 1/20 | 0.46 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | BID | P55957 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24301726 | 0.95 | ACE (0.52) | MAGI3SIRT5TACR1ACEECE1 | |
| SCHEMBL24301411 | 0.91 | MAGI3 (0.52) | MAGI3TACR1CASP1CASP3CASP7 | |
| SCHEMBL24301217 | 0.89 | MAGI3 (0.51) | MAGI3SIRT5TACR1CASP1CASP3 | |
| SCHEMBL24301742 | 0.89 | MAGI3 (0.52) | MAGI3SIRT5TACR1CASP1CASP3 | |
| SCHEMBL24301284 | 0.88 | NMBR (0.54) | MAGI3SIRT5TACR1CASP1CASP3 | |
| SCHEMBL24301412 | 0.88 | MAGI3 (0.49) | MAGI3TACR1CASP1CASP3CASP7 | |
| SCHEMBL24301398 | 0.88 | MAGI3 (0.48) | MAGI3SIRT5TACR1CASP1CASP3 | |
| SCHEMBL24301266 | 0.88 | MAGI3 (0.48) | MAGI3SIRT5TACR1CASP1CASP3 | |
| SCHEMBL22247784 | 0.87 | ALOX15 (0.59) | TACR1ACEECE1ALOX15 | |
| SCHEMBL24302207 | 0.86 | MMP9 (0.62) | MAGI3TACR1ACEECE1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022078462-A1 | NOVEL GLUTAMINE ANALOGS | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |