Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.54 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.54 |
| ▸ | KDM5A | P29375 | 2/20 | 0.52 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.52 |
| ▸ | PPARG | P37231 | 7/20 | 0.52 |
| ▸ | PPARD | Q03181 | 7/20 | 0.52 |
| ▸ | PPARA | Q07869 | 7/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.52 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24304809 | 1.00 | DGKA (0.54) | DGKADNM1KDM5APHF8KDM4C | |
| SCHEMBL15044736 | 1.00 | DGKA (0.54) | DGKADNM1KDM5APHF8KDM4C | |
| SCHEMBL24305234 | 1.00 | DGKA (0.54) | DGKADNM1KDM5APHF8KDM4C | |
| SCHEMBL23903371 | 0.95 | NAAA (0.51) | DGKADNM1GPR84PPARGPPARD | |
| SCHEMBL23903378 | 0.95 | NAAA (0.51) | DGKADNM1GPR84PPARGPPARD | |
| SCHEMBL25626482 | 0.94 | DGKA (0.59) | DGKADNM1KDM5APHF8KDM4C | |
| SCHEMBL27329950 | 0.92 | NAAA (0.58) | DGKADNM1TSHRALDH1A1NAAA | |
| SCHEMBL27329949 | 0.92 | NAAA (0.58) | DGKADNM1TSHRALDH1A1NAAA | |
| SCHEMBL19032431 | 0.91 | DGKA (0.54) | DGKADNM1KDM5APHF8KDM4C | |
| SCHEMBL19032457 | 0.91 | DGKA (0.59) | DGKADNM1KDM5APHF8KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357166-A1 | PIPERAZINE-BASED CATIONIC LIPIDS | TRANSLATE BIO, INC. | 2023-11-09 | — | — | US | disclosed |
| US-20230357166-A1 | PIPERAZINE-BASED CATIONIC LIPIDS | TRANSLATE BIO, INC. | 2023-11-09 | — | — | US | disclosed |
| WO-2023178167-A1 | ASYMMETRIC PIPERAZINE-BASED CATIONIC LIPIDS | TRANSLATE BIO, INC. (US) | 2023-09-21 | — | — | WO | disclosed |
| WO-2022066916-A1 | PIPERAZINE-BASED CATIONIC LIPIDS | TRANSLATE BIO, INC. (US) | 2022-03-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357166-A1 | PIPERAZINE-BASED CATIONIC LIPIDS | NPC1L1, SREBF2, NPC1 | DGKA 1007/4885DNM1 673/4885KDM5A 2386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.