SCHEMBL24304451

SCHEMBL24304451

CCCCCCCCCCCCCCCCCOCCCCOP(=O)(O)O[C@H]1O[C@@](C#N)(c2ccc3c(N)ncnn23)[C@H](O)[C@@H]1O

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ TMPRSS2 O15393 1/20 0.38
▸ POLRMT O00411 1/20 0.36
▸ FGFR1 P11362 1/20 0.35
▸ CYP3A4 P08684 4/20 0.33
▸ CYP2D6 P10635 4/20 0.33
▸ ADK P55263 3/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24305105 1.00 TMPRSS2 (0.38) TMPRSS2POLRMTFGFR1CYP3A4CYP2D6
SCHEMBL30464557 0.89 TMPRSS2 (0.37) TMPRSS2POLRMTFGFR1
SCHEMBL30464547 0.89 TMPRSS2 (0.37) TMPRSS2POLRMTFGFR1
SCHEMBL30464554 0.89 TMPRSS2 (0.37) TMPRSS2POLRMTFGFR1
SCHEMBL30464519 0.89 TMPRSS2 (0.37) TMPRSS2POLRMTFGFR1
SCHEMBL25968060 0.89 TMPRSS2 (0.42) TMPRSS2POLRMTFGFR1ADK
SCHEMBL25967624 0.89 TMPRSS2 (0.42) TMPRSS2POLRMTFGFR1ADK
SCHEMBL24304364 0.89 TMPRSS2 (0.42) TMPRSS2POLRMTFGFR1ADK
SCHEMBL24304414 0.88 TMPRSS2 (0.42) TMPRSS2POLRMTFGFR1ADK
SCHEMBL24304701 0.88 TMPRSS2 (0.42) TMPRSS2POLRMTFGFR1ADK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240025932-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2024-01-25 — — US disclosed
US-11773122-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES. INC. (US) 2023-10-03 — — US disclosed
US-20220081455-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2022-03-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220081455-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 TMPRSS2 310/4885POLRMT 371/4885FGFR1 4843/4885
US-20240025932-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 TMPRSS2 310/4885POLRMT 371/4885FGFR1 4843/4885
US-11773122-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS2, SGMS1 TMPRSS2 310/4885POLRMT 371/4885FGFR1 4843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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