Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24304283 | 0.85 | SLC6A4 (0.43) | SLC6A4QDPR | |
| SCHEMBL24304262 | 0.84 | SLC6A4 (0.43) | SLC6A4 | |
| SCHEMBL20934696 | 0.82 | TGFBR1 (0.47) | SLC6A4QDPR | |
| SCHEMBL30962901 | 0.78 | KDM4E (0.49) | SLC6A4QDPR | |
| SCHEMBL20200680 | 0.73 | SLC6A4 (0.50) | SLC6A4 | |
| SCHEMBL15490489 | 0.73 | QDPR (0.57) | QDPR | |
| SCHEMBL27227728 | 0.72 | SLC6A4 (0.46) | SLC6A4QDPR | |
| SCHEMBL10917066 | 0.72 | SLC6A4 (0.58) | SLC6A4QDPR | |
| SCHEMBL23122430 | 0.70 | SLC6A4 (0.46) | SLC6A4 | |
| SCHEMBL29745190 | 0.70 | SLC6A4 (0.46) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220119370-A1 | BRD4-JAK2 INHIBITORS | H. LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE, INC. | 2022-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220119370-A1 | BRD4-JAK2 INHIBITORS | BRD4, BICRA, JAK2 | SLC6A4 3915/4885QDPR 2173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.