SCHEMBL24304751

SCHEMBL24304751

CCCCCCCC/C=C\CCCCCCCCOC[C@@H](O)CO[Si](c1ccccc1)(c1ccccc1)C(C)(C)C

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ P2RY10 O00398 1/20 0.44
▸ USP2 O75604 1/20 0.43
▸ HTT P42858 1/20 0.39
▸ LPAR1 Q92633 2/20 0.39
▸ LPAR3 Q9UBY5 2/20 0.39
▸ LPAR5 Q9H1C0 1/20 0.38
▸ PPARG P37231 1/20 0.37
▸ PPARA Q07869 1/20 0.37
▸ DGKA P23743 1/20 0.36
▸ SOAT2 O75908 1/20 0.36
▸ SOAT1 P35610 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16520374 0.96 P2RY10 (0.44) P2RY10USP2HTTLPAR1LPAR3
SCHEMBL9698821 0.93 USP2 (0.49) P2RY10USP2HTTLPAR5SOAT1
SCHEMBL30866258 0.93 USP2 (0.49) P2RY10USP2HTTLPAR5SOAT1
SCHEMBL24304592 0.93 USP2 (0.49) P2RY10USP2HTTLPAR5SOAT1
SCHEMBL15096620 0.89 KDM4E (0.42) USP2HTTLPAR5
SCHEMBL6317349 0.87 ALDH1A1 (0.41) LPAR1LPAR3
SCHEMBL16520376 0.85 LPAR1 (0.39) LPAR1LPAR3PPARGPPARA
SCHEMBL16520357 0.84 LPAR1 (0.42) LPAR1LPAR3
SCHEMBL4341940 0.84 PPARG (0.41) LPAR1LPAR3PPARGPPARASOAT2
SCHEMBL4341938 0.84 PPARG (0.41) LPAR1LPAR3PPARGPPARASOAT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12030904-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES, INC. (US) 2024-07-09 — — US disclosed
US-12030904-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES, INC. (US) 2024-07-09 — — US disclosed
US-20240025932-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2024-01-25 — — US disclosed
US-20240025932-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2024-01-25 — — US disclosed
US-11773122-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES. INC. (US) 2023-10-03 — — US disclosed
US-11773122-B2 Phospholipid compounds and uses thereof GILEAD SCIENCES. INC. (US) 2023-10-03 — — US disclosed
US-20230250117-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2023-08-10 — — US disclosed
US-20230250117-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2023-08-10 — — US disclosed
US-20220081455-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF GILEAD SCIENCES, INC. 2022-03-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12030904-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS2, SGMS1 P2RY10 909/4885USP2 4298/4885HTT 3678/4885
US-20230250117-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 P2RY10 909/4885USP2 4298/4885HTT 3678/4885
US-20220081455-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 P2RY10 909/4885USP2 4298/4885HTT 3678/4885
US-20240025932-A1 PHOSPHOLIPID COMPOUNDS AND USES THEREOF PHOSPHO1, SGMS2, SGMS1 P2RY10 909/4885USP2 4298/4885HTT 3678/4885
US-11773122-B2 Phospholipid compounds and uses thereof PHOSPHO1, SGMS2, SGMS1 P2RY10 909/4885USP2 4298/4885HTT 3678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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