Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR39 | O43194 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29566600 | 0.82 | HTR1A (0.37) | GPR39 | |
| SCHEMBL24309632 | 0.82 | HTR1A (0.37) | GPR39 | |
| SCHEMBL24309688 | 0.81 | MAPK1 (0.46) | GPR39 | |
| SCHEMBL24309625 | 0.80 | TDP1 (0.38) | GPR39 | |
| SCHEMBL24310349 | 0.80 | GPR39 (0.35) | GPR39 | |
| SCHEMBL24310347 | 0.78 | GPR39 (0.39) | GPR39 | |
| SCHEMBL24309634 | 0.77 | CACNA1B (0.33) | GPR39 | |
| SCHEMBL24309787 | 0.76 | MAPT (0.36) | GPR39 | |
| SCHEMBL24309663 | 0.76 | GPR39 (0.37) | GPR39 | |
| SCHEMBL24309788 | 0.73 | GCK (0.36) | GPR39 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076627-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |