Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | PFKFB3 | Q16875 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24309801 | 0.86 | DRD2 (0.31) | EGFR | |
| SCHEMBL26807391 | 0.85 | HTR1A (0.37) | EGFR | |
| SCHEMBL29566863 | 0.85 | HTR1A (0.37) | EGFR | |
| SCHEMBL24310772 | 0.84 | HTR1A (0.33) | — | |
| SCHEMBL24310751 | 0.83 | MAP4K1 (0.34) | EGFR | |
| SCHEMBL24309803 | 0.83 | DRD3 (0.37) | EGFR | |
| SCHEMBL24310478 | 0.76 | BRD4 (0.32) | — | |
| SCHEMBL24310709 | 0.76 | DRD2 (0.33) | EGFR | |
| SCHEMBL24309230 | 0.74 | EGFR (0.32) | EGFR | |
| SCHEMBL24309527 | 0.73 | DRD2 (0.39) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076627-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |