⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9642740 | 0.74 | KDM4C (0.43) | — | |
| SCHEMBL6404716 | 0.73 | — | — | |
| SCHEMBL10063339 | 0.71 | — | — | |
| SCHEMBL23939813 | 0.71 | — | — | |
| SCHEMBL23939800 | 0.71 | — | — | |
| Water SCHEMBL6474736 | 0.71 | LDHA (0.37) | — | |
| SCHEMBL9642732 | 0.71 | HAO1 (0.36) | — | |
| SCHEMBL12050686 | 0.68 | HAO1 (0.35) | — | |
| SCHEMBL23939777 | 0.67 | HAO1 (0.37) | — | |
| SCHEMBL22678977 | 0.67 | L3MBTL1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022066933-A1 | PENTAFLUORO-SULFANYL -SUBSTITUTED TRIAZOLYL COMPOUNDS AND METHODS OF USE THEREOF | CHINOOK THERAPEUTICS CANADA, INC. (CA) | 2022-03-31 | — | — | WO | disclosed |