Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24309815 | 0.86 | JAK2 (0.34) | JAK2 | |
| SCHEMBL24310486 | 0.85 | JAK2 (0.32) | JAK2 | |
| SCHEMBL24309836 | 0.84 | JAK2 (0.33) | JAK2 | |
| SCHEMBL24309723 | 0.84 | JAK2 (0.34) | JAK2 | |
| SCHEMBL24309576 | 0.82 | JAK2 (0.33) | JAK2 | |
| SCHEMBL24309833 | 0.82 | JAK2 (0.32) | JAK2 | |
| SCHEMBL24309404 | 0.82 | CNR1 (0.35) | JAK2 | |
| SCHEMBL24310692 | 0.81 | JAK2 (0.33) | JAK2 | |
| SCHEMBL24309978 | 0.80 | HTR1A (0.35) | JAK2 | |
| SCHEMBL24309390 | 0.78 | JAK2 (0.31) | JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076627-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |