Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 2/20 | 0.32 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24310776 | 0.92 | CTSC (0.37) | CTSCMAP4K1TACR1IGF1R | |
| SCHEMBL24310186 | 0.92 | CTSC (0.35) | CTSCMAP4K1TACR1IGF1R | |
| SCHEMBL24310092 | 0.84 | MAP4K1 (0.31) | MAP4K1 | |
| SCHEMBL29566997 | 0.83 | RAD52 (0.34) | CTSCMAP4K1TACR1IGF1R | |
| SCHEMBL24310530 | 0.83 | RAD52 (0.34) | CTSCMAP4K1TACR1IGF1R | |
| SCHEMBL24309552 | 0.82 | MAPK7 (0.32) | — | |
| SCHEMBL24309562 | 0.82 | FLT4 (0.32) | — | |
| SCHEMBL24310094 | 0.80 | CTSC (0.39) | CTSCMAP4K1TACR1IGF1R | |
| SCHEMBL24310535 | 0.79 | PTK2 (0.31) | — | |
| SCHEMBL24310068 | 0.79 | EGFR (0.35) | CTSCMAP4K1IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022076627-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2022-04-14 | — | — | WO | disclosed |