Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 2/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HTR1F | P30939 | 4/20 | 0.32 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2431179 | 0.89 | KDM4E (0.35) | ADORA2BACKR3ALDH1A1HPGDTP53 | |
| SCHEMBL2435967 | 0.84 | NPSR1 (0.39) | ALDH1A1TP53KDM4EKMT2ANPC1 | |
| SCHEMBL2433596 | 0.84 | MAPT (0.36) | ALDH1A1TP53NPC1MAPTRAB9A | |
| SCHEMBL3814842 | 0.83 | IKBKB (0.38) | KDM4ENPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL2433357 | 0.83 | GRM4 (0.32) | — | |
| SCHEMBL2879446 | 0.77 | GRM5 (0.36) | KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL3807290 | 0.77 | HDAC6 (0.32) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL3807257 | 0.76 | KDM4E (0.39) | ALDH1A1HPGDKDM4EKMT2ANPC1 | |
| SCHEMBL2494792 | 0.76 | KDM4E (0.47) | ACKR3HPGDTP53KDM4EKMT2A | |
| SCHEMBL2494789 | 0.76 | KDM4E (0.47) | ACKR3HPGDTP53KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086966-B1 | 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI VIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-09-14 | — | — | EP | claimed |