Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2433596 | 0.90 | MAPT (0.36) | GRM4 | |
| SCHEMBL2428555 | 0.90 | GRM4 (0.31) | GRM4 | |
| SCHEMBL2429131 | 0.89 | GRM4 (0.33) | GRM4 | |
| SCHEMBL2435967 | 0.83 | NPSR1 (0.39) | — | |
| SCHEMBL2431182 | 0.83 | ADORA2B (0.35) | — | |
| SCHEMBL2433595 | 0.79 | GRM4 (0.36) | GRM4 | |
| SCHEMBL2431208 | 0.78 | MAPT (0.36) | GRM4 | |
| SCHEMBL2431283 | 0.77 | GRM4 (0.38) | GRM4 | |
| SCHEMBL2431286 | 0.77 | GRM4 (0.38) | GRM4 | |
| SCHEMBL2428166 | 0.77 | DGAT1 (0.36) | GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2086966-B1 | 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI VIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-09-14 | — | — | EP | claimed |